MAEL anticorps (AA 73-347) (Fluoro550)

N° du produit ABIN8007343

Cet anticorps anti-MAEL Polyclonal Lapin conjugué à Fluoro550 (ABIN8007343) détecte spécifiquement MAEL dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MAEL anticorps (AA 73-347) (Fluoro550) (ABIN8007343)

Antigène: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAEL est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-MAEL anticorps (Fluoro550)

Épitope: AA 73-347

Fonction: Anti-MAEL Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MAEL recombinant protein (Position: E73-Q347).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MAEL

Antigène: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Autre désignation: MAEL

Sujet:

Background: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.

Gene Full Name: maelstrom spermatogenic transposon silencer

ID gène: 84944

UniProt: Q96JY0