MEFV anticorps (N-Term) (Fluoro647)

N° du produit ABIN8008735

Cet anticorps anti-MEFV Polyclonal Lapin conjugué à Fluoro647 (ABIN8008735) détecte spécifiquement MEFV dans FACS. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour MEFV anticorps (N-Term) (Fluoro647) (ABIN8008735)

Antigène: MEFV (Mediterranean Fever (MEFV))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEFV est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-MEFV anticorps (Fluoro647)

Épitope: N-Term

Fonction: Anti-MEFV Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by eight amino acids,and from the related rat sequence by eleven amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human MEFV, different from the related mouse sequence by eight amino acids, and from the related rat sequence by eleven amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MEFV

Antigène: MEFV (Mediterranean Fever (MEFV))

Autre désignation: MEFV

Sujet:

Background: MEFV (Mediterranean fever) is a human gene that provides instructions for making a protein called pyrin (also known as marenostrin). Pyrin is produced in certain white blood cells (neutrophils, eosinophils and monocytes) that play a role in inflammation and in fighting infection. Inside these white blood cells, pyrin is found with thecytoskeleton, the structural framework that helps to define the shape, size, and movement of a cell. Pyrin's protein structure also allows it to interact with other molecules involved in fighting infection and in the inflammatory response. Although pyrin's function is not fully understood, it likely assists in keeping the inflammation process under control. Research indicates that pyrin helps regulate inflammation by interacting with the cytoskeleton. And Pyrin may the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed.

Gene Full Name: MEFV innate immunity regulator, pyrin

ID gène: 4210

UniProt: O15553

Pathways: Positive Regulation of Endopeptidase Activity