Melanophilin anticorps (AA 61-523) (Fluoro550)

N° du produit ABIN8008960

Cet anticorps anti-Melanophilin Polyclonal Lapin conjugué à Fluoro550 (ABIN8008960) détecte spécifiquement Melanophilin dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Melanophilin anticorps (AA 61-523) (Fluoro550) (ABIN8008960)

Antigène: Melanophilin (MLPH)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Melanophilin est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-Melanophilin anticorps (Fluoro550)

Épitope: AA 61-523

Fonction: Anti-MLPH Antibody Fluoro550 Conjugated

Homologie: Human Melanophilin,MLPH shares 61.6% amino acid (aa) sequence identity with mouse Melanophilin,MLPH.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Melanophilin/MLPH recombinant protein (Position: E61-L523). Human Melanophilin/MLPH shares 61.6% amino acid (aa) sequence identity with mouse Melanophilin/MLPH.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Melanophilin

Antigène: Melanophilin (MLPH)

Autre désignation: MLPH

Sujet:

Background: Melanophilin is a carrier protein which in humans is encoded by the MLPH gene. This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: melanophilin

ID gène: 79083

UniProt: Q9BV36