MBD4 anticorps (AA 16-580) (HRP)

N° du produit ABIN8009601

L’anticorps anti-MBD4 Polyclonal Lapin est utilisé pour la détection de MBD4 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour MBD4 anticorps (AA 16-580) (HRP) (ABIN8009601)

Antigène: MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBD4 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-MBD4 anticorps (HRP)

Épitope: AA 16-580

Fonction: Anti-MBD4/MED1 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MBD4/MED1 recombinant protein (Position: A16-S580).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MBD4

Antigène: MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

Autre désignation: MBD4

Sujet:

Background: Methyl-CpG-binding domain protein 4 is a protein that in humans is encoded by the MBD4 gene. It is mapped to 3q21.3. The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: methyl-CpG binding domain 4, DNA glycosylase

ID gène: 8930

UniProt: O95243

Pathways: Réparation de l'ADN