MBD4 anticorps (AA 238-534) (Fluoro550)

N° du produit ABIN8009609

Cet anticorps Lapin Polyclonal détecte spécifiquement MBD4 dans FACS. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour MBD4 anticorps (AA 238-534) (Fluoro550) (ABIN8009609)

Antigène: MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBD4 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-MBD4 anticorps (Fluoro550)

Épitope: AA 238-534

Fonction: Anti-Mbd4 Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Mouse Mbd4 shares 69.7% amino acid (aa) sequence identity with human MBD4.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Mbd4 recombinant protein (Position: R238-D534). Mouse Mbd4 shares 69.7% amino acid (aa) sequence identity with human MBD4.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MBD4

Antigène: MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

Autre désignation: Mbd4

Sujet:

Background: Methyl-CpG-binding domain protein 4 is a protein that in humans is encoded by the MBD4 gene. It is mapped to 3q21.3. The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: methyl-CpG binding domain protein 4

ID gène: 17193

UniProt: Q9Z2D7

Pathways: Réparation de l'ADN