MICB anticorps (N-Term) (Cy3)

N° du produit ABIN8009904

L’anticorps anti-MICB Polyclonal Lapin est utilisé pour la détection de MICB dans des échantillons de Humain et Souris. Il a été validé pour FACS.

Aperçu rapide pour MICB anticorps (N-Term) (Cy3) (ABIN8009904)

Antigène: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MICB est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-MICB anticorps (Cy3)

Épitope: N-Term

Fonction: Anti-MICB Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human MICB.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MICB

Antigène: MICB (MHC Class I Polypeptide-Related Sequence B (MICB))

Autre désignation: MICB

Sujet:

Background: MHC class I polypeptide-related sequence B is a protein that in humans is encoded by the MICB gene. This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Gene Full Name: MHC class I polypeptide-related sequence B

Sequence Similarities: Belongs to the MHC class I family. MIC subfamily.

ID gène: 4277

UniProt: Q29980

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response