MFGE8 anticorps (AA 23-463) (PE)

N° du produit ABIN8010220

Cet anticorps anti-MFGE8 Polyclonal Lapin conjugué à PE (ABIN8010220) détecte spécifiquement MFGE8 dans FACS. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour MFGE8 anticorps (AA 23-463) (PE) (ABIN8010220)

Antigène: MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MFGE8 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-MFGE8 anticorps (PE)

Épitope: AA 23-463

Fonction: Anti-Milk Fat Globule 1/Mfge8 Antibody PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Mouse?Mfge8 shares?86.2%?amino?acid?(aa)?sequence?identity?with rat Mfge8.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Milk Fat Globule 1/Mfge8 recombinant protein (Position: A23-C463). Mouse?Mfge8 shares?86.2%?amino?acid?(aa)?sequence?identity?with rat Mfge8.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MFGE8

Antigène: MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))

Autre désignation: Mfge8

Sujet:

Background: MFGE8 (Milk Fat Globule-Egf Factor 8), also called as Lactadherin or SED1, is a protein which in humans is encoded by the MFGE8 gene. Mfge8 is secreted protein found in vertebrates, including mammals as well as birds. By fluorescence in situ hybridization, Collins et al. (1997) mapped the MFGE8 gene to chromosome 15q25. Hanayama et al. (2002) found that MFGE8 is a factor that links apoptotic cells to phagocytes. MFGE8 specifically bound to apoptotic cells by recognizing aminophospholipids such as phosphatidylserine. MFGE8, when engaged by phospholipids, bound to cells via its RGD motif. It bound particularly strongly to cells expressing alpha-V-beta-3 integrin. Bu et al. (2007) showed that Mfge8 was expressed in intestinal lamina propria macrophages in mice. Using a wound-healing assay, they showed that Mfge8 promoted migration of intestinal epithelial cells through a PKC-epsilon (PRKCE)-dependent mechanism.

Gene Full Name: milk fat globule EGF and factor V/VIII domain containing

ID gène: 17304

UniProt: P21956

Pathways: SARS-CoV-2 Protein Interactome