MOG anticorps (Middle Region) (Fluoro550)

N° du produit ABIN8012382

L’anticorps anti-MOG Polyclonal Lapin est utilisé pour la détection de MOG dans des échantillons de Humain, Rat et Souris. Il a été validé pour FACS.

Aperçu rapide pour MOG anticorps (Middle Region) (Fluoro550) (ABIN8012382)

Antigène: MOG (Myelin Oligodendrocyte Glycoprotein (MOG))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MOG est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-MOG anticorps (Fluoro550)

Épitope: Middle Region

Fonction: Anti-Myelin oligodendrocyte glycoprotein/MOG Antibody Fluoro550 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human Myelin oligodendrocyte glycoprotein/MOG, which shares 85.7% and 88.6% amino acid (aa) sequence identity with mouse and rat Myelin oligodendrocyte glycoprotein/MOG, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MOG

Antigène: MOG (Myelin Oligodendrocyte Glycoprotein (MOG))

Autre désignation: MOG

Sujet:

Background: Myelin oligodendrocyte glycoprotein (MOG) is a glycoprotein believed to be important in the myelination of nerves in the central nervous system (CNS). In humans this protein is encoded by the MOG gene. This gene is mapped to 6p22.1. It is speculated to serve as a necessary adhesion molecule to provide structural integrity to the myelin sheath and is known to develop late on the oligodendrocyte. The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Full Name: myelin oligodendrocyte glycoprotein

ID gène: 4340

UniProt: Q16653