NADPH Oxidase 4 anticorps (C-Term) (HRP)

N° du produit ABIN8013762

L’anticorps anti-NADPH Oxidase 4 Polyclonal Lapin est utilisé pour la détection de NADPH Oxidase 4 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour NADPH Oxidase 4 anticorps (C-Term) (HRP) (ABIN8013762)

Antigène: NADPH Oxidase 4 (NOX4)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NADPH Oxidase 4 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-NADPH Oxidase 4 anticorps (HRP)

Épitope: C-Term

Fonction: Anti-NADPH oxidase 4/NOX4 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related rat sequence,different from the related human sequence by two amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of mouse NADPH oxidase 4, identical to the related rat sequence and different from the related human sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur NADPH Oxidase 4

Antigène: NADPH Oxidase 4 (NOX4)

Autre désignation: NOX4

Sujet:

Background: NADPH oxidase 4 is an enzyme that in humans is encoded by the NOX4 gene, and is a member of the NOX family of NADPH oxidases. This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

Gene Full Name: NADPH oxidase 4

Sequence Similarities: Contains 1 FAD-binding FR-type domain.

ID gène: 50490

UniProt: Q9JHI8

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration