Neurexin 1 anticorps (AA 141-294) (Fluoro550)

N° du produit ABIN8014562

Cet anticorps Lapin Polyclonal détecte spécifiquement Neurexin 1 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Neurexin 1 anticorps (AA 141-294) (Fluoro550) (ABIN8014562)

Antigène: Neurexin 1 (NRXN1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurexin 1 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-Neurexin 1 anticorps (Fluoro550)

Épitope: AA 141-294

Fonction: Anti-Neurexin 1/NRXN1 Antibody Fluoro550 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human Neurexin 1 recombinant protein (Position: D141-E294).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Neurexin 1

Antigène: Neurexin 1 (NRXN1)

Autre désignation: NRXN1

Sujet:

Background: Neurexin-1-alpha is a protein that in humans is encoded by the NRXN1 gene. This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca (2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.

Gene Full Name: neurexin 1

ID gène: 9378

UniProt: P58400

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development