Neurofibromin 1 anticorps (AA 160-270) (Cy3)
Aperçu rapide pour Neurofibromin 1 anticorps (AA 160-270) (Cy3) (ABIN8014681)
Antigène
Voir toutes Neurofibromin 1 (NF1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 160-270
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Fonction
- Anti-Neurofibromin/NF1 Antibody Cy3 Conjugated
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Neurofibromin/NF1 recombinant protein (Position: R160-Q270).
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Isotype
- IgG
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Indications d'application
- Flow Cytometry, 1-3 μg/1x106 cells
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Date de péremption
- 12 months
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- Neurofibromin 1 (NF1)
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Autre désignation
- NF1
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Sujet
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Background: Neurofibromin 1 (NF1) is a gene in humans that is located on chromosome 17. This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.
Gene Full Name: neurofibromin 1
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ID gène
- 4763
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UniProt
- P21359
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Pathways
- cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
Antigène
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