Neuropilin 1 anticorps (AA 504-827) (PE)

N° du produit ABIN8015084

Cet anticorps Souris Monoclonal détecte spécifiquement Neuropilin 1 dans FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour Neuropilin 1 anticorps (AA 504-827) (PE) (ABIN8015084)

Antigène: Neuropilin 1 (NRP1)

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Neuropilin 1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: 4G3F7

Détail du produit anti-Neuropilin 1 anticorps (PE)

Épitope: AA 504-827

Fonction: Anti-Neuropilin 1 Antibody (monoclonal, 4G3F7) PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Human Neuropilin 1 shares 95%,94% amino acid (aa) sequences identity with mouse,rat Neuropilin 1,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Neuropilin 1 recombinant protein (Position: K504-T827). Human Neuropilin 1 shares 95% and 94% amino acid (aa) sequences identity with mouse and rat Neuropilin 1, respectively.

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Neuropilin 1

Antigène: Neuropilin 1 (NRP1)

Autre désignation: NRP1

Sujet:

Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contain a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Gene Full Name: neuropilin 1

ID gène: 8829

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals