NLRP7 anticorps (AA 1-169) (PE)

N° du produit ABIN8015931

L’anticorps anti-NLRP7 Polyclonal Lapin est utilisé pour la détection de NLRP7 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour NLRP7 anticorps (AA 1-169) (PE) (ABIN8015931)

Antigène: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP7 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-NLRP7 anticorps (PE)

Épitope: AA 1-169

Fonction: Anti-NLRP7 Antibody PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NLRP7 recombinant protein (Position: M1-L169).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur NLRP7

Antigène: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Autre désignation: NLRP7

Sujet:

Background: NACHT, LRR and PYD domains-containing protein 7 is a protein that in humans is encoded by the NLRP7 gene. This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: NLR family pyrin domain containing 7

ID gène: 199713

UniProt: Q8WX94

Pathways: Inflammasome