NUMA1 anticorps (AA 1-1954) (HRP)

N° du produit ABIN8016689

Cet anticorps Lapin Polyclonal détecte spécifiquement NUMA1 dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour NUMA1 anticorps (AA 1-1954) (HRP) (ABIN8016689)

Antigène: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUMA1 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-NUMA1 anticorps (HRP)

Épitope: AA 1-1954

Fonction: Anti-NUMA/NUMA1 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NUMA/NUMA1 recombinant protein (Position: M1-E1954).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur NUMA1

Antigène: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Autre désignation: NUMA1

Sujet:

Background: Nuclear mitotic apparatus protein 1 is a protein that in humans is encoded by the NUMA1 gene. This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.

Gene Full Name: nuclear mitotic apparatus protein 1

ID gène: 4926

UniProt: Q14980

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase