OCRL anticorps (AA 1-901)

N° du produit ABIN8017926

L’anticorps anti-OCRL Polyclonal Lapin est utilisé pour la détection de OCRL dans des échantillons de Humain. Il a été validé pour WB, ELISA, IHC, IF et ICC.

Aperçu rapide pour OCRL anticorps (AA 1-901) (ABIN8017926)

Antigène: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OCRL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Classe de qualité: Carrier-free

Détail du produit anti-OCRL anticorps

Épitope: AA 1-901

Fonction: Anti-OCRL Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-OCRL Antibody. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human OCRL recombinant protein (Position: M1-D901).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur OCRL

Antigène: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Autre désignation: OCRL

Sujet:

Background: Inositol polyphosphate 5-phosphatase OCRL-1, also known as Lowe oculocerebrorenal syndrome protein, is an enzyme encoded by the OCRL gene located on the X chromosome in humans. This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.

Gene Full Name: OCRL inositol polyphosphate-5-phosphatase

Poids moléculaire: 104 kDa

ID gène: 4952

UniProt: Q01968

Pathways: Inositol Metabolic Process