ORC2 anticorps (AA 130-493) (Fluoro550)

N° du produit ABIN8018372

Cet anticorps Lapin Polyclonal détecte spécifiquement ORC2 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ORC2 anticorps (AA 130-493) (Fluoro550) (ABIN8018372)

Antigène: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ORC2 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-ORC2 anticorps (Fluoro550)

Épitope: AA 130-493

Fonction: Anti-ORC2 Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human ORC2 shares 80.2%,79.4% amino acid (aa) sequence identity with mouse,rat ORC2,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ORC2 recombinant protein (Position: E130-R493). Human ORC2 shares 80.2% and 79.4% amino acid (aa) sequence identity with mouse and rat ORC2, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ORC2

Antigène: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Autre désignation: ORC2

Sujet:

Background: Origin recognition complex subunit 2 is a protein that is encoded by the ORC2 (ORC2L) gene in humans. The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate.

Gene Full Name: origin recognition complex subunit 2

ID gène: 4999

UniProt: Q13416