Otoferlin anticorps (C-Term) (Fluoro594)

N° du produit ABIN8018605

Cet anticorps anti-Otoferlin Polyclonal Lapin conjugué à Fluoro594 (ABIN8018605) détecte spécifiquement Otoferlin dans FACS. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour Otoferlin anticorps (C-Term) (Fluoro594) (ABIN8018605)

Antigène: Otoferlin (OTOF)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Otoferlin est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-Otoferlin anticorps (Fluoro594)

Épitope: C-Term

Fonction: Anti-Otoferlin Antibody Fluoro594 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Otoferlin, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Otoferlin

Antigène: Otoferlin (OTOF)

Autre désignation: OTOF

Sujet:

Background: Otoferlin is a protein that in humans is encoded by the OTOF gene. Mutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of the encoded protein has three C2 domains, a single carboxy-terminal transmembrane domain found also in the C. elegans spermatogenesis factor FER-1 and human dysferlin, while the long form has six C2 domains. The homology suggests that this protein may be involved in vesicle membrane fusion. Several transcript variants encoding multipleisoforms have been found for this gene.

Gene Full Name: otoferlin

Sequence Similarities: Belongs to the ferlin family.

ID gène: 9381

UniProt: Q9HC10

Pathways: Sensory Perception of Sound, Synaptic Vesicle Exocytosis