OTUD5 anticorps (AA 168-555) (HRP)

N° du produit ABIN8018640

L’anticorps anti-OTUD5 Polyclonal Lapin est utilisé pour la détection de OTUD5 dans des échantillons de Humain et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour OTUD5 anticorps (AA 168-555) (HRP) (ABIN8018640)

Antigène: OTUD5 (OTU Domain Containing 5 (OTUD5))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OTUD5 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-OTUD5 anticorps (HRP)

Épitope: AA 168-555

Fonction: Anti-OTUD5 Antibody HRP Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human OTUD5 shares 98.2%,98.5% amino acid (aa) sequence identity with mouse,rat OTUD5,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human OTUD5 recombinant protein (Position: R168-D555). Human OTUD5 shares 98.2% and 98.5% amino acid (aa) sequence identity with mouse and rat OTUD5, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur OTUD5

Antigène: OTUD5 (OTU Domain Containing 5 (OTUD5))

Autre désignation: OTUD5

Sujet:

Background: OTU deubiquitinase 5 is a protein that in humans is encoded by the OTUD5 gene. This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Full Name: OTU deubiquitinase 5

ID gène: 55593

UniProt: Q96G74