OTUD5 anticorps (AA 168-555)

N° du produit ABIN8018644

Cet anticorps anti-OTUD5 Polyclonal Lapin (ABIN8018644) détecte spécifiquement OTUD5 dans WB, ELISA, IF et ICC. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour OTUD5 anticorps (AA 168-555) (ABIN8018644)

Antigène: OTUD5 (OTU Domain Containing 5 (OTUD5))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OTUD5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Classe de qualité: Carrier-free

Détail du produit anti-OTUD5 anticorps

Épitope: AA 168-555

Fonction: Anti-OTUD5 Antibody

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human OTUD5 shares 98.2%,98.5% amino acid (aa) sequence identity with mouse,rat OTUD5,respectively.

Attributs du produit: Anti-OTUD5 Antibody. Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human OTUD5 recombinant protein (Position: R168-D555). Human OTUD5 shares 98.2% and 98.5% amino acid (aa) sequence identity with mouse and rat OTUD5, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur OTUD5

Antigène: OTUD5 (OTU Domain Containing 5 (OTUD5))

Autre désignation: OTUD5

Sujet:

Background: OTU deubiquitinase 5 is a protein that in humans is encoded by the OTUD5 gene. This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Full Name: OTU deubiquitinase 5

Poids moléculaire: 75 kDa

ID gène: 55593

UniProt: Q96G74