HRPT2 anticorps (AA 119-520) (Fluoro550)

N° du produit ABIN8019453

L’anticorps anti-HRPT2 Polyclonal Lapin est utilisé pour la détection de HRPT2 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour HRPT2 anticorps (AA 119-520) (Fluoro550) (ABIN8019453)

Antigène: HRPT2 (CDC73) (Parafibromin (CDC73))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRPT2 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-HRPT2 anticorps (Fluoro550)

Épitope: AA 119-520

Fonction: Anti-HRPT2/CDC73 Antibody Fluoro550 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human HRPT2 shares 100%,99.8% amino acid (aa) sequence identity with mouse,rat HRPT2,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HRPT2 recombinant protein (Position: Q119-R520). Human HRPT2 shares 100% and 99.8% amino acid (aa) sequence identity with mouse and rat HRPT2, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur HRPT2

Antigène: HRPT2 (CDC73) (Parafibromin (CDC73))

Autre désignation: CDC73

Sujet:

Background: Cell division cycle 73, also known as HRPT2, is a protein which in humans is encoded by the CDC73 gene. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. And this protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.

Gene Full Name: cell division cycle 73

Sequence Similarities: Belongs to the CDC73 family.

ID gène: 79577

UniProt: Q6P1J9

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance