PAM anticorps (AA 69-914) (HRP)

N° du produit ABIN8020268

Cet anticorps Lapin Polyclonal détecte spécifiquement PAM dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PAM anticorps (AA 69-914) (HRP) (ABIN8020268)

Antigène: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAM est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PAM anticorps (HRP)

Épitope: AA 69-914

Fonction: Anti-PAM Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PAM shares 97.4% amino acid (aa) sequence identity with mouse PAM.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PAM recombinant protein (Position: K69-R914). Human PAM shares 97.4% amino acid (aa) sequence identity with mouse PAM.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PAM

Antigène: PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))

Autre désignation: PAM

Sujet:

Background: This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Gene Full Name: peptidylglycine alpha-amidating monooxygenase

ID gène: 5066

UniProt: P19021