PER1 anticorps (AA 1119-1200) (PE)

N° du produit ABIN8020513

Cet anticorps anti-PER1 Polyclonal Lapin conjugué à PE (ABIN8020513) détecte spécifiquement PER1 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PER1 anticorps (AA 1119-1200) (PE) (ABIN8020513)

Antigène: PER1 (Period Homolog 1 (Drosophila) (PER1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PER1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-PER1 anticorps (PE)

Épitope: AA 1119-1200

Fonction: Anti-PER1 Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human PER1 recombinant protein (Position: D1119-M1200).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PER1

Antigène: PER1 (Period Homolog 1 (Drosophila) (PER1))

Autre désignation: PER1

Sujet:

Background: The PER1 gene encodes the period circadian protein homolog 1 protein in humans. This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene, however, these variants have not been fully described.

Gene Full Name: period circadian regulator 1

ID gène: 5187

UniProt: O15534

Pathways: Photoperiodism