Peroxiredoxin 2 anticorps (AA 5-127) (Biotin)

N° du produit ABIN8020594

Cet anticorps anti-Peroxiredoxin 2 Polyclonal Lapin conjugué à Biotin (ABIN8020594) détecte spécifiquement Peroxiredoxin 2 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Peroxiredoxin 2 anticorps (AA 5-127) (Biotin) (ABIN8020594)

Antigène: Peroxiredoxin 2 (PRDX2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Peroxiredoxin 2 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Peroxiredoxin 2 anticorps (Biotin)

Épitope: AA 5-127

Fonction: Anti-peroxiredoxin 2/PRDX2 Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human peroxiredoxin 2/PRDX2 recombinant protein (Position: N5-R127).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Peroxiredoxin 2

Antigène: Peroxiredoxin 2 (PRDX2)

Autre désignation: PRDX2

Sujet:

Background: PRDX2(peroxiredoxin 2) also known as NKEFB, PRP, PRX2, PRXII or TPX1, is a?protein?that in humans is encoded by the?PRDX2?gene. This gene encodes a member of the peroxiredoxin family of antioxidant?enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides.?The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The?Prdx2?-/- mice were healthy in appearance and fertile. Choi et al.(2005)?demonstrated that?PRDX2?is a negative regulator of PDGF signaling. Prx II deficiency results in increased production of peroxide, enhanced activation of PDGF receptor and phospholipase C-gamma-1, and subsequently increased cell proliferation and migration in response to PDGF. PRX2 accounted for about half of the thioredoxin activity in parasite extracts, and PRX2 expression was increased in the presence of chloroquine, regardless of P. falciparum strain susceptibility to the drug.

Gene Full Name: peroxiredoxin 2

ID gène: 7001

UniProt: P32119