PEX19 anticorps (AA 51-269) (FITC)

N° du produit ABIN8020766

Cet anticorps Lapin Polyclonal détecte spécifiquement PEX19 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PEX19 anticorps (AA 51-269) (FITC) (ABIN8020766)

Antigène: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PEX19 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-PEX19 anticorps (FITC)

Épitope: AA 51-269

Fonction: Anti-PEX19 Antibody FITC Conjugated

Homologie: Human PEX19 shares 91.8%,94.5% amino acid (aa) sequence identity with mouse,rat PEX19,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PEX19 recombinant protein (Position: Q51-A269). Human PEX19 shares 91.8% and 94.5% amino acid (aa) sequence identity with mouse and rat PEX19, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PEX19

Antigène: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Autre désignation: PEX19

Sujet:

Background: Peroxisomal biogenesis factor 19 is a protein that in humans is encoded by the PEX19 gene. This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

Gene Full Name: peroxisomal biogenesis factor 19

ID gène: 5824

UniProt: P40855