PDE12 anticorps (AA 36-607)

N° du produit ABIN8021409

L’anticorps anti-PDE12 Polyclonal Lapin est utilisé pour la détection de PDE12 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, FACS et ELISA.

Aperçu rapide pour PDE12 anticorps (AA 36-607) (ABIN8021409)

Antigène: PDE12 (Phosphodiesterase 12 (PDE12))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE12 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Classe de qualité: Carrier-free

Détail du produit anti-PDE12 anticorps

Épitope: AA 36-607

Fonction: Anti-PDE12 Antibody

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PDE12 shares 89.9%,91.3% amino acid (aa) sequence identity with mouse,rat PDE12,respectively.

Attributs du produit: Anti-PDE12 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PDE12 recombinant protein (Position: E36-K607). Human PDE12 shares 89.9% and 91.3% amino acid (aa) sequence identity with mouse and rat PDE12, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PDE12

Antigène: PDE12 (Phosphodiesterase 12 (PDE12))

Autre désignation: PDE12

Sujet:

Background: PDE12 is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. It also cleaves 3',5'-phosphodiester bond of oligoadenylates and plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.

Gene Full Name: phosphodiesterase 12

Poids moléculaire: 70 kDa

ID gène: 201626

UniProt: Q6L8Q7