PDE8A anticorps (AA 32-495) (Fluoro594)

N° du produit ABIN8021550

L’anticorps anti-PDE8A Polyclonal Lapin est utilisé pour la détection de PDE8A dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour PDE8A anticorps (AA 32-495) (Fluoro594) (ABIN8021550)

Antigène: PDE8A (phosphodiesterase 8A (PDE8A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE8A est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-PDE8A anticorps (Fluoro594)

Épitope: AA 32-495

Fonction: Anti-PDE8A Antibody Fluoro594 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PDE8A shares 80.5% amino acid (aa) sequence identity with mouse PDE8A.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PDE8A recombinant protein (Position: R32-E495). Human PDE8A shares 80.5% amino acid (aa) sequence identity with mouse PDE8A.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PDE8A

Antigène: PDE8A (phosphodiesterase 8A (PDE8A))

Autre désignation: PDE8A

Sujet:

Background: High affinity cAMP-specific and IBMX-insensitive 3', 5'-cyclic phosphodiesterase 8A is an enzyme that in humans is encoded by the PDE8A gene. The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: phosphodiesterase 8A

ID gène: 5151

UniProt: O60658

Pathways: cAMP Metabolic Process