PDE8A anticorps (AA 32-495)
Aperçu rapide pour PDE8A anticorps (AA 32-495) (ABIN8021556)
Antigène
Voir toutes PDE8A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 32-495
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Fonction
- Anti-PDE8A Antibody
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Réactivité croisée (Details)
- No cross reactivity with other proteins.
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Homologie
- Human PDE8A shares 80.5% amino acid (aa) sequence identity with mouse PDE8A.
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Attributs du produit
- Anti-PDE8A Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human PDE8A recombinant protein (Position: R32-E495). Human PDE8A shares 80.5% amino acid (aa) sequence identity with mouse PDE8A.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- PDE8A (phosphodiesterase 8A (PDE8A))
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Autre désignation
- PDE8A
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Sujet
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Background: High affinity cAMP-specific and IBMX-insensitive 3', 5'-cyclic phosphodiesterase 8A is an enzyme that in humans is encoded by the PDE8A gene. The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: phosphodiesterase 8A
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Poids moléculaire
- 93 kDa
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ID gène
- 5151
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UniProt
- O60658
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Pathways
- cAMP Metabolic Process
Antigène
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