PFKM anticorps (AA 39-780) (APC)

N° du produit ABIN8021621

Cet anticorps Lapin Polyclonal détecte spécifiquement PFKM dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PFKM anticorps (AA 39-780) (APC) (ABIN8021621)

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFKM est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-PFKM anticorps (APC)

Épitope: AA 39-780

Fonction: Anti-PFKM Antibody APC Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PFKM shares 97.7%,96.8% amino acid (aa) sequence identity with mouse,rat PFKM,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PFKM recombinant protein (Position: R39-V780). Human PFKM shares 97.7% and 96.8% amino acid (aa) sequence identity with mouse and rat PFKM, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PFKM

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Autre désignation: PFKM

Sujet:

Background: 6-phosphofructokinase, muscle type is an enzyme that in humans is encoded by the PFKM gene on chromosome 12. Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.

Gene Full Name: phosphofructokinase, muscle

ID gène: 5213

UniProt: P08237

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, L'effet Warburg