PLA2G4A anticorps (C-Term)
Aperçu rapide pour PLA2G4A anticorps (C-Term) (ABIN8022022)
Antigène
Voir toutes PLA2G4A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- C-Term
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Fonction
- Anti-Phospholipase A2/PLA2G4A Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Homologie
- different from the related mouse,rat sequences by three amino acids.
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Attributs du produit
- Anti-Phospholipase A2/PLA2G4A Antibody. Tested in WB applications. This antibody reacts with Human, Mouse.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of human PLA2G4A, different from the related mouse and rat sequences by three amino acids.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL, Human, Mouse
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))
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Autre désignation
- PLA2G4A
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Sujet
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Background: PLA2G4A (Phospholipase A2, Group IVA), is an enzyme that in humans is encoded by the PLA2G4A gene. Tay et al. (1995) mapped the PLA2G4A gene to rat chromosome 13 by PCR-based intercross genotyping and to human 1q25 by fluorescence in situ hybridization. By site-ed mutagenesis and biochemical analysis of the recombinant protein, Sharp et al. (1994) determined that ser228 participates in the catalytic mechanism of cPLA2 and that both the phospholipase A2 and the lysophospholipase activities are catalyzed by the same active site residue (s). PLA2G4A, the cytosolic phospholipase A2, appears to subserve transmembrane signaling responses to extracellular ligands (Skorecki, 1995).
Gene Full Name: phospholipase A2 group IVA
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Poids moléculaire
- 85 kDa
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ID gène
- 5321
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UniProt
- P47712
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Pathways
- Inositol Metabolic Process, G-protein mediated Events, VEGF Signaling
Antigène
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