PNN anticorps (AA 2-241) (Fluoro594)

N° du produit ABIN8022594

L’anticorps anti-PNN Polyclonal Lapin est utilisé pour la détection de PNN dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour PNN anticorps (AA 2-241) (Fluoro594) (ABIN8022594)

Antigène: PNN (Pinin, Desmosome Associated Protein (PNN))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNN est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-PNN anticorps (Fluoro594)

Épitope: AA 2-241

Fonction: Anti-PNN/DRSP Antibody Fluoro594 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PNN/DRSP recombinant protein (Position: A2-L241).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PNN

Antigène: PNN (Pinin, Desmosome Associated Protein (PNN))

Autre désignation: PNN

Sujet:

Background: Pinin is a protein that in humans is encoded by the PNN gene. By yeast 2-hybrid analysis of HeLa cells, followed by sequence analysis, it was found that epitope-tagged human PNN interacted with the serine/arginine (SR)-rich proteins SRP75 (SRSF4, 601940), SRM300 (SRRM2, 606032), and SRRP130 (PNISR, 616653). Truncation analysis revealed that the polyserine/RS domain of PNN and flanking sequences participated in binding to these SR proteins. The 4 proteins colocalized in the nucleus of HCE-T cells, and overexpression of any of these proteins affected the distribution of the others between nuclear speckles and nucleoplasm.

Gene Full Name: pinin, desmosome associated protein

ID gène: 5411

UniProt: Q9H307