Pleiotrophin anticorps (AA 61-148) (Fluoro594)

N° du produit ABIN8023439

Cet anticorps Lapin Polyclonal détecte spécifiquement Pleiotrophin dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Pleiotrophin anticorps (AA 61-148) (Fluoro594) (ABIN8023439)

Antigène: Pleiotrophin (PTN)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Pleiotrophin est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-Pleiotrophin anticorps (Fluoro594)

Épitope: AA 61-148

Fonction: Anti-PTN Antibody Fluoro594 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PTN recombinant protein (Position: D61-K148).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Pleiotrophin

Antigène: Pleiotrophin (PTN)

Autre désignation: PTN

Sujet:

Background: Pleiotrophin (PTN), also known as heparin-binding brain mitogen (HBBM) or heparin-binding growth factor 8 (HBGF-8) or neurite growth-promoting factor 1 (NEGF1) or heparin affinity regulatory peptide (HARP) or heparin binding growth associated molecule (HB-GAM), is a protein that in humans is encoded by the PTN gene. PTN is the first member of a family of developmentally regulated cytokines. The PTN gene is mapped to 7q33-q34. A mutant PTN that contained only the first N-terminal 40 amino acids was a dominant negative. Pleiotrophin is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. Pleiotrophin binds to cell-surface nucleolin as a low affinity receptor. This binding can inhibit HIV infection.

Gene Full Name: pleiotrophin

ID gène: 5764

UniProt: P21246

Pathways: Signalisation RTK