POLI anticorps (C-Term) (PE)

N° du produit ABIN8024073

L’anticorps anti-POLI Polyclonal Lapin est utilisé pour la détection de POLI dans des échantillons de Humain, Rat et Souris. Il a été validé pour FACS.

Aperçu rapide pour POLI anticorps (C-Term) (PE) (ABIN8024073)

Antigène: POLI (Polymerase (DNA Directed) iota (POLI))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLI est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-POLI anticorps (PE)

Épitope: C-Term

Fonction: Anti-DNA Polymerase iota/POLI Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human DNA Polymerase iota, which shares 70.6% and 76.5% amino acid (aa) sequence identity with mouse and rat DNA Polymerase iota, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur POLI

Antigène: POLI (Polymerase (DNA Directed) iota (POLI))

Autre désignation: POLI

Sujet:

Background: DNA polymerase iota is an enzyme that in humans is encoded by the POLI gene. The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass the lesion.

Gene Full Name: DNA polymerase iota

ID gène: 11201

UniProt: Q9UNA4

Pathways: Réparation de l'ADN