PTRF anticorps (AA 47-390) (Cy3)

N° du produit ABIN8024354

Cet anticorps Lapin Polyclonal détecte spécifiquement PTRF dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PTRF anticorps (AA 47-390) (Cy3) (ABIN8024354)

Antigène: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTRF est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-PTRF anticorps (Cy3)

Épitope: AA 47-390

Fonction: Anti-PTRF/CAVIN1 Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PTRF/CAVIN1 recombinant protein (Position: D47-D390).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PTRF

Antigène: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Autre désignation: CAVIN1

Sujet:

Background: This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.

Gene Full Name: caveolae associated protein 1

ID gène: 284119

UniProt: Q6NZI2