PNKP anticorps (AA 43-487) (Cy3)

N° du produit ABIN8024387

Cet anticorps Lapin Polyclonal détecte spécifiquement PNKP dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PNKP anticorps (AA 43-487) (Cy3) (ABIN8024387)

Antigène: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNKP est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-PNKP anticorps (Cy3)

Épitope: AA 43-487

Fonction: Anti-PNKP Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PNKP shares 81.8% amino acid (aa) sequence identity with mouse PNKP.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PNKP recombinant protein (Position: D43-E487). Human PNKP shares 81.8% amino acid (aa) sequence identity with mouse PNKP.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PNKP

Antigène: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Autre désignation: PNKP

Sujet:

Background: This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

Gene Full Name: polynucleotide kinase 3'-phosphatase

ID gène: 11284

UniProt: Q96T60

Pathways: Réparation de l'ADN, Nucleotide Phosphorylation