PARL anticorps (Middle Region) (Biotin)

N° du produit ABIN8025207

L’anticorps anti-PARL Polyclonal Lapin est utilisé pour la détection de PARL dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA, WB et IHC.

Aperçu rapide pour PARL anticorps (Middle Region) (Biotin) (ABIN8025207)

Antigène: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARL est conjugé à/à la Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PARL anticorps (Biotin)

Épitope: Middle Region

Fonction: Anti-PARL Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PARL shares 98.8% amino acid (aa) sequence identity with both mouse,rat PARL.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human PARL. Human PARL shares 98.8% amino acid (aa) sequence identity with both mouse and rat PARL.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PARL

Antigène: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Autre désignation: PARL

Sujet:

Background: This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.

Gene Full Name: presenilin associated rhomboid like

ID gène: 55486

UniProt: Q9H300

Pathways: Autophagy