PARL anticorps (Middle Region) (Fluoro594)

N° du produit ABIN8025211

Cet anticorps anti-PARL Polyclonal Lapin conjugué à Fluoro594 (ABIN8025211) détecte spécifiquement PARL dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PARL anticorps (Middle Region) (Fluoro594) (ABIN8025211)

Antigène: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARL est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-PARL anticorps (Fluoro594)

Épitope: Middle Region

Fonction: Anti-PARL Antibody Fluoro594 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PARL shares 98.8% amino acid (aa) sequence identity with both mouse,rat PARL.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human PARL. Human PARL shares 98.8% amino acid (aa) sequence identity with both mouse and rat PARL.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PARL

Antigène: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Autre désignation: PARL

Sujet:

Background: This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.

Gene Full Name: presenilin associated rhomboid like

ID gène: 55486

UniProt: Q9H300

Pathways: Autophagy