Prostate Specific Antigen anticorps (AA 25-261)

N° du produit ABIN8026457

Cet anticorps Lapin Polyclonal détecte spécifiquement Prostate Specific Antigen dans IHC et WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Prostate Specific Antigen anticorps (AA 25-261) (ABIN8026457)

Antigène: Prostate Specific Antigen (PSA)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prostate Specific Antigen est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Classe de qualité: Carrier-free

Détail du produit anti-Prostate Specific Antigen anticorps

Épitope: AA 25-261

Fonction: Anti-Prostate Specific Antigen/KLK3 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PSA shares 54% amino acid (aa) sequence identity with rat PSA.

Attributs du produit: Anti-Prostate Specific Antigen/KLK3 Antibody. Tested in IHC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PSA recombinant protein (Position: I25-P261). Human PSA shares 54% amino acid (aa) sequence identity with rat PSA.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 1-2 μg/mL, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Prostate Specific Antigen

Antigène: Prostate Specific Antigen (PSA)

Autre désignation: KLK3

Sujet:

Background: Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. KLK3 is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. This gene is mapped to 19q13.33. KLK3 is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. KLK3 is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving the cervical mucous cap, allowing the entry of sperm. It is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia.

Gene Full Name: kallikrein related peptidase 3

Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

Poids moléculaire: 29 kDa

ID gène: 354

UniProt: P07288

Pathways: Système du Complément