PRMT6 anticorps (AA 45-348) (PE)

N° du produit ABIN8027121

L’anticorps anti-PRMT6 Polyclonal Lapin est utilisé pour la détection de PRMT6 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour PRMT6 anticorps (AA 45-348) (PE) (ABIN8027121)

Antigène: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRMT6 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-PRMT6 anticorps (PE)

Épitope: AA 45-348

Fonction: Anti-PRMT6 Antibody PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PRMT6 recombinant protein (Position: Q45-D348).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PRMT6

Antigène: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Autre désignation: PRMT6

Sujet:

Background: Protein arginine N-methyltransferase 6 is an enzyme that in humans is encoded by the PRMT6 gene. The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.

Gene Full Name: protein arginine methyltransferase 6

ID gène: 55170

UniProt: Q96LA8