PCDHGA2 anticorps (AA 132-444) (Fluoro488)

N° du produit ABIN8028738

L’anticorps anti-PCDHGA2 Polyclonal Lapin est utilisé pour la détection de PCDHGA2 dans des échantillons de Humain et Souris. Il a été validé pour FACS.

Aperçu rapide pour PCDHGA2 anticorps (AA 132-444) (Fluoro488) (ABIN8028738)

Antigène: PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHGA2 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-PCDHGA2 anticorps (Fluoro488)

Épitope: AA 132-444

Fonction: Anti-PCDHGA2 Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PCDHGA2 shares 60.3% amino acid (aa) sequence identity with mouse PCDHGA2.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PCDHGA2 recombinant protein (Position: R132-D444). Human PCDHGA2 shares 60.3% amino acid (aa) sequence identity with mouse PCDHGA2.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PCDHGA2

Antigène: PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))

Autre désignation: PCDHGA2

Sujet:

Background: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Gene Full Name: protocadherin gamma subfamily A, 2

ID gène: 56113

UniProt: Q9Y5H1