PNP anticorps (AA 44-273) (HRP)

N° du produit ABIN8028973

Cet anticorps anti-PNP Polyclonal Lapin conjugué à HRP (ABIN8028973) détecte spécifiquement PNP dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour PNP anticorps (AA 44-273) (HRP) (ABIN8028973)

Antigène: PNP (Purine Nucleoside Phosphorylase (PNP))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNP est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PNP anticorps (HRP)

Épitope: AA 44-273

Fonction: Anti-PNP Antibody HRP Conjugated

Homologie: Human PNP shares 86.5%,87% amino acid (aa) sequence identity with mouse,rat PNP,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PNP recombinant protein (Position: Q44-Q273). Human PNP shares 86.5% and 87% amino acid (aa) sequence identity with mouse and rat PNP, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PNP

Antigène: PNP (Purine Nucleoside Phosphorylase (PNP))

Autre désignation: PNP

Sujet:

Background: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.

Gene Full Name: purine nucleoside phosphorylase

ID gène: 4860

UniProt: P00491

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus