RAB13 anticorps (C-Term) (APC)

N° du produit ABIN8029614

L’anticorps anti-RAB13 Polyclonal Lapin est utilisé pour la détection de RAB13 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour RAB13 anticorps (C-Term) (APC) (ABIN8029614)

Antigène: RAB13 (RAB13, Member RAS Oncogene Family (RAB13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB13 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-RAB13 anticorps (APC)

Épitope: C-Term

Fonction: Anti-RAB13 Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse,rat sequences by four amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human RAB13, different from the related mouse and rat sequences by four amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur RAB13

Antigène: RAB13 (RAB13, Member RAS Oncogene Family (RAB13))

Autre désignation: RAB13

Sujet:

Background: Ras-related protein Rab-13 is a protein that in humans is encoded by the RAB13 gene. This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12.

Gene Full Name: RAB13, member RAS oncogene family

ID gène: 5872

UniProt: P51153

Pathways: Cell-Cell Junction Organization