RAB7A anticorps (AA 21-177) (PE)

N° du produit ABIN8029971

L’anticorps anti-RAB7A Polyclonal Lapin est utilisé pour la détection de RAB7A dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour RAB7A anticorps (AA 21-177) (PE) (ABIN8029971)

Antigène: RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB7A est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-RAB7A anticorps (PE)

Épitope: AA 21-177

Fonction: Anti-RAB7/RAB7A Antibody PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RAB7/RAB7A recombinant protein (Position: K21-E177).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur RAB7A

Antigène: RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))

Autre désignation: RAB7A

Sujet:

Background: Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene. RAB7A functions as a key regulator in endo-lysosomal trafficking, governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end ed endosomal migration and positions, and endosome-lysosome transport through different protein-protein interaction cascades. Furthermore, RAB7A is involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes through modulation of SOX10 and the oncogene MYC. Mutations in the lysosomal pathway result in tumor progression in melanoma cells.

Gene Full Name: RAB7A, member RAS oncogene family

ID gène: 7879

UniProt: P51149

Pathways: EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome