RP2 anticorps (AA 244-348) (Biotin)

N° du produit ABIN8031729

L’anticorps anti-RP2 Monoclonal Souris est utilisé pour la détection de RP2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour RP2 anticorps (AA 244-348) (Biotin) (ABIN8031729)

Antigène: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RP2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 3D7

Détail du produit anti-RP2 anticorps (Biotin)

Épitope: AA 244-348

Fonction: Anti-RP2 Antibody (monoclonal, 3D7) Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human RP2recombinant protein (Position: D244-M348).

Isotype: IgG2b

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RP2

Antigène: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Autre désignation: RP2

Sujet:

Background: Protein XRP2 is a protein that in humans is encoded by the RP2 gene. It is mapped to Xp11.3. The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death.The RP2 protein is also involved in regulating the function and extension of outer segment of cone photoreceptors in mice.

Gene Full Name: RP2 activator of ARL3 GTPase

ID gène: 6102

UniProt: O75695

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process