GRAF anticorps (AA 584-791) (HRP)

N° du produit ABIN8032123

Cet anticorps anti-GRAF Polyclonal Lapin conjugué à HRP (ABIN8032123) détecte spécifiquement GRAF dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GRAF anticorps (AA 584-791) (HRP) (ABIN8032123)

Antigène: GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRAF est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-GRAF anticorps (HRP)

Épitope: AA 584-791

Fonction: Anti-GRAF/ARHGAP26 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GRAF/ARHGAP26 recombinant protein (Position: S584-E791).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GRAF

Antigène: GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))

Autre désignation: ARHGAP26

Sujet:

Background: Rho GTPase activating protein 26 (ARHGAP26) also known as GTPase Regulator Associated with Focal Adhesion Kinase (GRAF) is a protein that in humans is encoded by the ARHGAP26 gene. Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: Rho GTPase activating protein 26

ID gène: 23092

UniProt: Q9UNA1