RRBP1 anticorps (C-Term) (PE)

N° du produit ABIN8033094

L’anticorps anti-RRBP1 Polyclonal Lapin est utilisé pour la détection de RRBP1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour RRBP1 anticorps (C-Term) (PE) (ABIN8033094)

Antigène: RRBP1 (Ribosome Binding Protein 1 (RRBP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRBP1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-RRBP1 anticorps (PE)

Épitope: C-Term

Fonction: Anti-RRBP1 Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human RRBP1, which shares 87.2% and 89.4% amino acid (aa) sequence identity with mouse and rat RRBP1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur RRBP1

Antigène: RRBP1 (Ribosome Binding Protein 1 (RRBP1))

Autre désignation: RRBP1

Sujet:

Background: Ribosome-binding protein 1, also referred to as p180, is a protein that in humans is encoded by the RRBP1 gene. It is mapped to 20p12.1. This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12.

Gene Full Name: ribosome binding protein 1

ID gène: 6238

UniProt: Q9P2E9