SGCA anticorps (AA 24-387) (HRP)

N° du produit ABIN8034542

Cet anticorps Lapin Polyclonal détecte spécifiquement SGCA dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SGCA anticorps (AA 24-387) (HRP) (ABIN8034542)

Antigène: SGCA (Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SGCA est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SGCA anticorps (HRP)

Épitope: AA 24-387

Fonction: Anti-alpha Sarcoglycan/SGCA Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human SGCA shares 90.7% amino acid (aa) sequence identity with mouse SGCA.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SGCA recombinant protein (Position: Q24-H387). Human SGCA shares 90.7% amino acid (aa) sequence identity with mouse SGCA.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SGCA

Antigène: SGCA (Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA))

Autre désignation: SGCA

Sujet:

Background: Alpha-sarcoglycan is a protein that in humans is encoded by the SGCA gene. This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: sarcoglycan alpha

Sequence Similarities: Belongs to the sarcoglycan alpha/epsilon family.

ID gène: 6442

UniProt: Q16586