SLFN11 anticorps (AA 114-794) (Cy3)

N° du produit ABIN8034736

Cet anticorps anti-SLFN11 Polyclonal Lapin conjugué à Cy3 (ABIN8034736) détecte spécifiquement SLFN11 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SLFN11 anticorps (AA 114-794) (Cy3) (ABIN8034736)

Antigène: SLFN11 (Schlafen Family Member 11 (SLFN11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLFN11 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-SLFN11 anticorps (Cy3)

Épitope: AA 114-794

Fonction: Anti-SLFN11 Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SLFN11 recombinant protein (Position: P114-D794).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SLFN11

Antigène: SLFN11 (Schlafen Family Member 11 (SLFN11))

Autre désignation: SLFN11

Sujet:

Background: Schlafen family member 11 is a protein that in humans is encoded by the SLFN11 gene. SLFN11 is a nuclear protein that belongs to the Schlafen (SLFN) family of genes involved in cell cycle regulation and growth inhibition. Expression of SLFN11 predicts sensitivity of cancer cell lines to DNA-damaging agents. Evidence suggests that in the presence of DNA-targeted therapies, SLFN11 is recruited to stressed replication forks where it blocks replication leading to cell death. SLFN11 is being explored as a predictive biomarker for response to DNA-targeted therapies.

Gene Full Name: schlafen family member 11

ID gène: 91607

UniProt: Q7Z7L1