SEC31A anticorps (AA 101-806) (HRP)

N° du produit ABIN8034983

Cet anticorps Lapin Polyclonal détecte spécifiquement SEC31A dans ELISA, WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SEC31A anticorps (AA 101-806) (HRP) (ABIN8034983)

Antigène: SEC31A (SEC31 Homolog A (SEC31A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEC31A est conjugé à/à la HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SEC31A anticorps (HRP)

Épitope: AA 101-806

Fonction: Anti-SEC31A Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SEC31A recombinant protein (Position: Y101-K806).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SEC31A

Antigène: SEC31A (SEC31 Homolog A (SEC31A))

Autre désignation: SEC31A

Sujet:

Background: Protein transport protein Sec31A is a protein that in humans is encoded by the SEC31A gene. The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: SEC31 homolog A, COPII component

ID gène: 22872

UniProt: O94979

Pathways: ER-Nucleus Signaling