SEC63 anticorps (AA 37-760) (Fluoro647)

N° du produit ABIN8035019

Cet anticorps Lapin Polyclonal détecte spécifiquement SEC63 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SEC63 anticorps (AA 37-760) (Fluoro647) (ABIN8035019)

Antigène: SEC63 (SEC63 Homolog (SEC63))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEC63 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-SEC63 anticorps (Fluoro647)

Épitope: AA 37-760

Fonction: Anti-SEC63 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human SEC63 shares 96.1% amino acid (aa) sequence identity with mouse SEC63.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SEC63 recombinant protein (Position: R37-D760). Human SEC63 shares 96.1% amino acid (aa) sequence identity with mouse SEC63.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SEC63

Antigène: SEC63 (SEC63 Homolog (SEC63))

Autre désignation: SEC63

Sujet:

Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

Gene Full Name: SEC63 protein translocation regulator

ID gène: 11231

UniProt: Q9UGP8

Pathways: ER-Nucleus Signaling