SFRP4 anticorps (AA 140-346) (HRP)

N° du produit ABIN8035115

Cet anticorps Lapin Polyclonal détecte spécifiquement SFRP4 dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour SFRP4 anticorps (AA 140-346) (HRP) (ABIN8035115)

Antigène: SFRP4 (Secreted Frizzled-Related Protein 4 (SFRP4))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SFRP4 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-SFRP4 anticorps (HRP)

Épitope: AA 140-346

Fonction: Anti-SFRP4 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human SFRP4 shares 90%,90.3% amino acid (aa) sequence identity with mouse,rat SFRP4,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SFRP4 recombinant protein (Position: E140-V346). Human SFRP4 shares 90% and 90.3% amino acid (aa) sequence identity with mouse and rat SFRP4, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SFRP4

Antigène: SFRP4 (Secreted Frizzled-Related Protein 4 (SFRP4))

Autre désignation: SFRP4

Sujet:

Background: Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. It is mappaead to 7p14.1. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. And SFRP4 is a hub gene in a Type 2 Diabetes-associated gene coexpression module in human islets, and reduces glucose-induced insulin secretion through decreased β-cell exocytosis.

Gene Full Name: secreted frizzled related protein 4

Sequence Similarities: Belongs to the secreted frizzled-related protein (sFRP) family.

ID gène: 6424

UniProt: Q6FHJ7

Pathways: Signalisation WNT